2 results for "5-HT7 Receptor Antagonists Small Molecules and Peptides" in Products

5-HT7 Receptor Antagonists Small Molecules and Peptides

Serotonin 5-HT7 receptors are located primarily in the thalamus, hypothalamus and hippocampus. The function of these receptors includes the regulation of circadian rhythms, learning and memory and smooth muscle relaxation. The human 5-HT7 receptor gene has been localized to chromosome 10 (10q21-24).

Potent and selective 5-HT7 antagonist; brain penetrant

Chemical Name: (2R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine hydrochloride
Purity: ≥98%
Potent and selective 5-HT7 antagonist; brain penetrant
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High affinity and selective 5-HT7 antagonist; orally bioavailable

Chemical Name: 6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride
Purity: ≥98%
High affinity and selective 5-HT7 antagonist; orally bioavailable
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