Potent and selective 5-HT7
receptor antagonist (pKi
values are 8.9, 7.2 and 6.0 for 5-HT7A
and < 6.0 for 5-HT1A
receptors respectively). Brain penetrant in vivo
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Characterization of SB-269970-A, a selective 5-HT7 receptor antagonist.
Hagan et al.
DR4004, a putative 5-HT7 receptor antagonist, also has functional activity at the dopamine receptor.
Kogan et al.
A novel, potent, and selective 5-HT7 antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)
Lovell et al.
The citations listed below are publications that use Tocris products. Selected citations for SB 269970 hydrochloride include:
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