4 results for "TrkB Small Molecules and Peptides" in Products
TrkB Small Molecules and Peptides
Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth.
Potent TrkB agonist
| Chemical Name: | N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide |
| Purity: | ≥98% |
TrkB agonist
| Alternate Names: | 7,8-DHF |
| Chemical Name: | 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
TrkB and TrkC agonist; brain penetrant
| Chemical Name: | 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol |
| Purity: | ≥97% |
Selective TrkB receptor agonist; neuroprotectant
| Chemical Name: | N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide |
| Purity: | ≥98% |
