6 results for "Activin RIB/ALK-4 Small Molecules and Peptides" in Products

Activin RIB/ALK-4 Small Molecules and Peptides

Receptors for the TGF-beta superfamily comprise two groups, the type I and the type II serine/threonine kinases. These kinases are type I transmembrane proteins, and the two subgroups are distinguished by the presence of a glycine/serine-rich juxta-membrane domain found in the type I receptors. Either a type I or type II receptor may initially bind...

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Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)
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SB 431542 synthesized to cGMP guidelines

Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
SB 431542 synthesized to cGMP guidelines
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Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity: ≥98%
Adult Stem Cell-derived Liver Organoids
(6)
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Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridine
Purity: ≥98%
Selective inhibitor of TGF-βRI, ALK4 and ALK7
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ALK4 and ALK5 (TGFβRI) inhibitor

Alternate Names: LY 2157299
Chemical Name: 4-[5,6-Dihydro-2-(6-methyl-2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide
Purity: ≥98%
ALK4 and ALK5 (TGFβRI) inhibitor
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Potent TGF-βRI inhibitor

Chemical Name: 4-[[4-[(2.6-Dimethyl-3-pyridinyl)oxy]-2-pyridinyl]amino]benzenesulfonamide
Purity: ≥98%
Potent TGF-βRI inhibitor
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