4 results for "ATM Small Molecules and Peptides" in Products

ATM Small Molecules and Peptides

Germline mutations in the Ataxia Telangiectasia-mutated (ATM) gene lead to the multi-symptom disorder A-T (Ataxia Telangiectasia). Immunodeficiency, neurodegeneration, premature aging, sensitivity to ionizing radiation, and a predisposition to certain types of cancer characterize A-T. The protein product of the gene mutated in A-T is a large prot...

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Potent and selective ATM kinase inhibitor

Chemical Name: 2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one
Purity: ≥98%
Potent and selective ATM kinase inhibitor
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Potent and selective ATM kinase inhibitor; orally bioavailable

Chemical Name: 7-Fluoro-6-[6-(methoxymethyl)-3-pyridinyl]-4-[[(1S)-1-(1-methyl-1H-pyrazol-3-yl)ethyl]amino]-3-quinolinecarboxamide
Purity: ≥98%
Potent and selective ATM kinase inhibitor; orally bioavailable
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Inhibitor of PI 3-kinase, mTOR and DNA-PK

Chemical Name: 3-[4-(4-Morpholinylpyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenol hydrochloride
Purity: ≥98%
Inhibitor of PI 3-kinase, mTOR and DNA-PK
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Potent and selective allosteric inhibitor of Wip1 phosphatase

Chemical Name: 5-[[(5-Chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cycloprpylamino)-2-oxoethyl]-2-thiophenecarboxamide
Purity: ≥98%
Potent and selective allosteric inhibitor of Wip1 phosphatase
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