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4 results for "beta-Catenin Compounds" in Products
beta-Catenin Compounds
β-catenin protein is an integral part of the canonical Wnt signaling pathway. Wnt binding to Frizzled (Fz) receptors and LRP co-receptors activates Dishevelled (Dsh) proteins; these in turn inhibit the destruction complex responsible for degrading β-catenin, which includes GSK-3, adenomatous polyposis coli (APC) and axin. Accumulation of β-catenin in the cell cytoplasm prompts its translocation to the nucleus, where it interacts with members of the TCF/LEF family of ...
| Chemical Name: | 5-[[2,5-Dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedion |
| Purity: | ≥98% |
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| Chemical Name: | 2-Phenoxybenzoic acid-[(5-methyl-2-furanyl)methylene]hydrazide |
| Purity: | ≥98% |
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| Chemical Name: | 5-(Phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)benzene sulfonamide hydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
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