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12 results for "Calcineurin" in Products
Calcineurin Products
Calcineurin, also called Protein Phosphatase 2B, PP2B, PPP2B, Protein Phosphatase 3, and PPP3, is an enzyme that dephosphorylates serine and threonine residues in proteins. It is a heterodimer of a 59,000 dalton catalytic A subunit and a 19,000 dalton regulatory B subunit that is activated by the binding of calcium ions and calmodulin. Calcineurin ...
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse, Rat, Bovine |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
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| Reactivity: | Human, Mouse, Rat, Bovine |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
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| Reactivity: | Human |
| Sensitivity: | 0.055 ng/mL (example only; lot dependent) |
| Assay Range: | 0.156 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
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| Reactivity: | Human |
| Sensitivity: | 0.055 ng/mL (example only; lot dependent) |
| Assay Range: | 0.156 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
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| Reactivity: | Rat |
| Sensitivity: | 0.055 ng/mL (example only; lot dependent) |
| Assay Range: | 0.156 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
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| Reactivity: | Mouse |
| Sensitivity: | 0.060 ng/mL (example only; lot dependent) |
| Assay Range: | 0.156 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
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Substrate for Calcineurin, PP1, PP2A, PP2C, and Ser/Thr phosphatases
| Reactivity: | Multi-Species |
| Applications: |
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Calcineurin inhibitor
| Alternate Names: | Ciclosporin A |
| Purity: | ≥98% |
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Potent calcineurin inhibitor; immunosuppressant
| Alternate Names: | Tacrolimus,Fujimycin |
| Chemical Name: | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone |
| Purity: | ≥98% |
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Inhibitor of calcineurin-mediated NFAT activation
| Alternate Names: | VIVIT peptide |
| Purity: | ≥95% |
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Inhibitor of calcineurin-substrate association
| Chemical Name: | 9,10-Dihydro-9,10[1',2']-benzenoanthracene-1,4-dione |
| Purity: | ≥95% |
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