3 results for "CFTR" in Products

CFTR Products

Cystic fibrosis transmembrane conductance regulator (CFTR) is a multi-pass transmembrane protein that functions as a chloride channel. CFTR belongs to the ATP-binding cassette (ABC) superfamily. Mutations in CFTR cause the pulmonary disease, cystic fibrosis (CF). Specifically, deletion of phenyalanine at position 508 (DeltaF508-CFTR) results in a f...

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Voltage-independent, selective CFTR chloride channel blocker

Chemical Name: 4-[[4-Oxo-2-thioxo-3-[3-trifluoromethyl)phenyl]-5-thiazolidinylidene]methyl]benzoic acid
Purity: ≥98%
Voltage-independent, selective CFTR chloride channel blocker
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Reversible, voltage-dependent CFTR chloride channel blocker

Chemical Name: N-2-Naphthalenyl-2-[(3,5-dibromo-2,4-dihydroxyphenyl)methylene]glycine hydrazide
Purity: ≥97%
Reversible, voltage-dependent CFTR chloride channel blocker
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Inhibits calcium-sensitive chloride currents

Chemical Name: 5-Nitro-2-(3-phenylpropylamino)benzoic acid
Purity: ≥98%
Inhibits calcium-sensitive chloride currents
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