NPPB

Tocris Bioscience | Catalog # 0593

Inhibits calcium-sensitive chloride currents
Tocris Bioscience

Key Product Details

Description

Inhibits calcium-sensitive chloride currents
View all Calcium-activated Chloride Channel Blockers »

Product Description

Inhibits calcium-sensitive chloride currents (10 μM). Putative GPR35 agonist.

Product Specifications for NPPB

Molecular Weight

300.31

Formula

C16H16N2O4

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

5-Nitro-2-(3-phenylpropylamino)benzoic acid

CAS Number

107254-86-4

PubChem ID

4549

InChI Key

WBSMIPAMAXNXFS-UHFFFAOYSA-N

SMILES

OC(=O)C1=CC(=CC=C1NCCCC1=CC=CC=C1)[N+]([O-])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 30.03 100
Ethanol 6.01 20

Preparing Stock Solutions for NPPB

The following data is based on the product molecular weight 300.31.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.33 mL 16.65 mL 33.30 mL
5 mM 0.67 mL 3.33 mL 6.66 mL
10 mM 0.33 mL 1.66 mL 3.33 mL
50 mM 0.07 mL 0.33 mL 0.67 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 70 publications citing the usage of this product.

Product Documents for NPPB

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for NPPB

For research use only

Customer Reviews for NPPB (1)

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  • A potent chloride channel blocker
    Name: Anonymous
    Species: Rat
    Assay Type: Ex Vivo
    Verified Customer | Posted 02/19/2018
    It blocks calcium-activated chloride currents. We used NPPB at 50-100 microM to block chloride channels. It dissolves well in DMSO

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