3 results for "Chk1 Small Molecules and Peptides" in Products

Chk1 Small Molecules and Peptides

The Chk1 checkpoint kinase is an integral member of the signaling cascade that controls cell cycle progression. In response to genotoxic stress, Chk1 is phosphorylated by ATM or ATM-related kinases. In turn, Chk1 phosphorylates downstream effectors, such as p53 or the Cdc25 phosphatases to halt cell cycle progression and allow time for repair of ...

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Chk1 inhibitor

Chemical Name: 9,10,11,12-Tetrahydro- 9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-1,3(2H)-dione
Purity: ≥98%
Chk1 inhibitor
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Potent and selective inhibitor of Chk1 and Wee1

Chemical Name: 9-Hydroxy-4-phenyl-pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
Purity: ≥98%
Potent and selective inhibitor of Chk1 and Wee1
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Potent and selective Chk1 inhibitor

Chemical Name: N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy)phenyl]-N'-(5-methyl-2-pyrazinyl)urea
Purity: ≥98%
Potent and selective Chk1 inhibitor
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