3 results for "cIAP-2/HIAP-1 Proteome Profiler Antibody Arrays" in Products
cIAP-2/HIAP-1 Proteome Profiler Antibody Arrays
cIAP-2 (also known as MIHC and HIAP-1) is a member of the inhibitor of apoptosis (IAP) family of proteins that inhibit the proteolytic activity of mature caspases. cIAP-2 has 3 BIR (baculovirus inhibitor of apoptosis) domains, a RING finger domain, and a caspase recruitment domain (CARD). cIAP-2 inhibits caspases through the direct interaction of its BIR domain with the active caspase. Caspase activity may be restored through interactions with the Reaper like motif on mitochondrial proteins such as SMAC/Diablo or HtrA2/Omi. cIAP-2 is reported to be cleaved by HtrA2/Omi.
Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies
| Reactivity: | Human |
| Applications: |
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
| Reactivity: | Human |
| Applications: |
Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
| Reactivity: | Human |
| Applications: |
