CRBN Products

Pomalidomide 4'-alkylC3-acid

Catalog #: 7096

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Chemical Name:	4-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]butanoic acid
Purity:	≥95%

Pomalidomide 4'-PEG2-acid

Catalog #: 7212

Product Documents

Cereblon ligand with PEG linker and terminal acid for onward chemistry

Chemical Name:	3-[2-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]propanoic acid
Purity:	≥95%

Pomalidomide 4'-PEG1-azide

Catalog #: 7434

Product Documents

Cereblon ligand with PEG linker and terminal azide for onward chemistry

Chemical Name:	4-[[2-(2-Azidoethoxy)ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity:	≥95%

Pomalidomide 4'-alkylC2-azide

Catalog #: 7439

Product Documents

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Chemical Name:	4-[(2-Azidoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity:	≥95%

Lenalidomide 5'-piperazine-4-methylpiperidine

Catalog #: 7473

Product Documents

Cereblon ligand with terminal piperidine for onward chemistry

Chemical Name:	3-[1,3-Dihydro-1-oxo-5-[4-(4-piperidinylmethyl)-1-piperazinyl]-2H-isoindol-2-yl]-2,6-piperidinedione dihydrochloride
Purity:	≥94%

Thalidomide 4'-oxyacetamide-alkylC4-azide

Catalog #: 6300

Product Documents

Cereblon ligand with alkyl linker and terminal azide for onward chemistry

Alternate Names:	Azido-Thalidomide
Chemical Name:	N-(4-Azidobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide
Purity:	≥98%

Thalidomide-4-hydroxyacetate

Catalog #: 6466

Product Documents

Carboxylic acid-functionalized Thalidomide; cereblon ligand for PROTACs

Chemical Name:	2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetic acid
Purity:	≥98%

Thalidomide 4'-oxyacetamide-PEG3-amine

Catalog #: 6467

(1)

Product Documents

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 1
Chemical Name:	N-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Purity:	≥95%

Thalidomide 4'-ether-alkylC6-amine

Catalog #: 6627

(1)

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 4
Chemical Name:	4-[(6-Aminohexyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Pomalidomide 4'-PEG2-amine

Catalog #: 6637

(1)

Product Documents

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	Pomalidomide - linker 1
Chemical Name:	4-[[2-[2-(2-Aminoethoxy)ethoxy]ethyl]amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
Purity:	≥95%

Pomalidomide 4'-alkylC5-acid

Catalog #: 6682

Product Documents

Cereblon ligand with alkyl linker and terminal acid for onward chemistry

Alternate Names:	Pomalidomide - linker 3
Chemical Name:	6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexanoic acid
Purity:	≥95%

Thalidomide, propargyl

Catalog #: 6685

Product Documents

Alkyne-functionalized Thalidomide; 'click' cereblon ligand for PROTACs

Chemical Name:	2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-yloxy)-1H-isoindole-1,3(2H)-dione
Purity:	≥95%

Thalidomide 4'-ether-PEG2-alkyne

Catalog #: 6686

Product Documents

Cereblon ligand with PEG linker and terminal alkyne for onward chemistry

Alternate Names:	Thalidomide - linker 5
Chemical Name:	2-(2,6-Dioxo-3-piperidinyl)-4-[2-[2-(2-propyn-1-yloxy)oxy]ethoxy]-1H-isoindole-1,3(2H)dione
Purity:	≥95%

Pomalidomide 4'-alkylC5-amine

Catalog #: 6716

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	Pomalidomide - linker 4
Chemical Name:	4-[(5-Aminopentyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Thalidomide 4'-ether-alkylC2-amine

Catalog #: 6850

Citations (10)

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 6
Chemical Name:	4-(2-Aminoethoxy)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Pomalidomide 4'-alkylC2-amine

Catalog #: 6851

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	Pomalidomide - linker 7
Chemical Name:	4-[(2-Aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Thalidomide 4'-oxyacetamide-alkylC1-PEG3-alkylC3-amine

Catalog #: 6913

Product Documents

Cereblon ligand with alkyl-PEG-alkyl linker and terminal amine for onward chemistry

Chemical Name:	N-[3-[2-[2-(3-Aminopropoxy)ethoxy]ethoxy]propyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Purity:	≥95%

Thalidomide 4'-ether-alkylC4-amine

Catalog #: 6917

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 9
Chemical Name:	4-(4-Aminobutoxy)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Pomalidomide 4'-alkylC8-amine

Catalog #: 6944

Citations (2)

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name:	4-[(8-Aminooctyl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Thalidomide 4'-oxyacetamide-alkylC8-amine

Catalog #: 6946

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Chemical Name:	N-(8-Aminooctyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-acetamide hydrochloride
Purity:	≥95%

Thalidomide 4'-oxyacetamide-alkylC2-amine

Catalog #: 6949

Product Documents

Cereblon ligand with alkyl linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 10
Chemical Name:	N-(2-Aminoethyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Purity:	≥95%

Thalidomide 4'-ether-PEG3-amine

Catalog #: 6950

Product Documents

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 11
Chemical Name:	4-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Thalidomide 4'-ether-PEG5-amine

Catalog #: 6951

Product Documents

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 12
Chemical Name:	4-((17-Amino-3,6,9,12,15-pentaoxaheptadecyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
Purity:	≥95%

Pomalidomide 4'-PEG4-amine

Catalog #: 6963

(1)

Product Documents

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	Pomalidomide - linker 8
Chemical Name:	4-[(14-Amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-1H-Isoindole-1,3(2H)-dione hydrochloride
Purity:	≥95%

Thalidomide 4'-oxyacetamide-PEG1-amine

Catalog #: 6966

Product Documents

Cereblon ligand with PEG linker and terminal amine for onward chemistry

Alternate Names:	Thalidomide - linker 13
Chemical Name:	N-[2-(2-Aminoethoxy)ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide
Purity:	≥95%