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4 results for "CRBN" in Products

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CRBN Products

Modulates cell surface expression of KCNT1 . May be involved in memory and learning

Catalog #: 6305

(1)

Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase

Chemical Name:	3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Purity:	≥98%

Catalog #: 7288

High affinity cereblon fluorescent probe

Chemical Name:	2-((1E,3E)-5-((E)-1-(6-((4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate
Purity:	≥90%

Catalog #: 7633

High affinity fluorescent probe for TR-FRET cereblon binding assay

Chemical Name:	3-(5,5-Difluoro-7,9-dimethyl-5H-5λ⁴,6λ⁴-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide
Purity:	≥95%

Catalog #: 7851

Molecular glue; induces degradation of NQAT1

Alternate Names:	Selective NTAQ1 degrader
Chemical Name:	3-[6-[(Fluorosulfonyl)oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione
Purity:	≥95%

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