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5 results for "DEK" in Products
DEK Products
The DEK oncogene is an approximately 45 kDa phosphoprotein with pleiotropic activities. It is a chromatin remodeling factor, a transcriptional coactivator and corepressor, a component of RNA spliceosomes, and a promoter of DNA repair during apoptosis. DEK is upregulated in many cancers and promotes epithelial cell transformation. It functions as a proinflammatory factor when secreted by activated macrophages. It is an autoantigen in juvenile arthritis and lupus and a target of chromosomal translocation with the CAN gene in acute myelogenous leukemia. DEK contains one SAP domain (aa 149-183), one nuclear localization sequence (aa 205-221), and a DNA-binding C-terminal domain (aa 321-375).
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #715524 |
| Applications: | IHC, WB |
![Human DEK Antibody (715524) [Alexa Fluor® 350]](https://resources.rndsystems.com/images/icons/RnD-Default-Product-Image_Antibodies-Icon.svg "Human DEK Antibody (715524) [Alexa Fluor® 350]"){kind=icon}
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| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #715511 |
| Applications: | IHC, ICC/IF |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, IP |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
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