3 results for "Dopamine D5R/DRD5" in Products

Dopamine D5R/DRD5 Products

DRD5 is the D5 subtype of the dopamine receptor, a G protein-coupled receptor which stimulates adenylyl cyclase. DRD5 is expressed in neurons in the limbic regions of the brain and has a 10-fold higher affinity for dopamine than the D1 subtype. DRD5 shows a trafficking profile distinct from that of any of the other dopamine receptors. Endocytosis of DRD5 can be achieved both homologously, through direct receptor activation by agonist, and also heterologously, due to independent activation of protein kinase C (PKC).

Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker

Alternate Names: (R)-(+)-SCH 23390 hydrochloride
Chemical Name: (R)-(+)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride
Purity: ≥98%
Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker
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High affinity D1-like antagonist

Alternate Names: Ecopipam hydrobromide
Chemical Name: (6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide
Purity: ≥98%
High affinity D1-like antagonist
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Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent

Chemical Name: (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate
Purity: ≥98%
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
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