4 results for "ErbB3/Her3 Small Molecules and Peptides" in Products

ErbB3/Her3 Small Molecules and Peptides

ErbB3, also called Her3 (human epidermal growth factor receptor 3) in humans, is a type I transmembrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB3 binds neuregulins NRG1 and NRG2, but lacks a working kinase domain; heterodimerization with another ErbB receptor is required for signaling. ErbB3 is important...

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EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor

Alternate Names: Tyrphostin AG 490
Chemical Name: (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide
Purity: ≥98%
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
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Negative control for PP 2 (Cat. No. 1407)

Chemical Name: 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: ≥98%
Negative control for PP 2 (Cat. No. 1407)
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Potent ErbB receptor family inhibitor

Chemical Name: N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine
Purity: ≥98%
Potent ErbB receptor family inhibitor
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Potent EGFR PROTAC® Degrader

Alternate Names: Iressa-based PROTAC 3
Chemical Name: (2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)pentyl)oxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98%
Potent EGFR PROTAC®
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