3 results for "ERR gamma/NR3B3 Small Molecules and Peptides" in Products

ERR gamma/NR3B3 Small Molecules and Peptides

Estrogen-related receptor alpha (ERR-alpha, ERR1, ESRL1; NR3B1) is a member of the orphan nuclear receptor family. ERR-alpha is expressed in the liver, kidney, brain, heart, uterus, vagina and cervix. ERR-alpha takes part in the cell cycle and the fatty acid metabolizing of the musculus skeleti. ERR-alpha was shown to interact with ER-alpha. ERR-beta (ERR2; NR3B2) is also expressed in the liver, brain, uterus, vagina, and cervix. ERR-beta has a role in early placental development. ERR-gamma (ESRRG; NR3B3) is expressed in the brain, kidney, testis, lung, adrenal gland, pancreas, placenta and bone marrow. ERR-gamma was shown to be located in the critical region for Usher's syndrome.

Potent pan-ERR agonist

Chemical Name: (E)-4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide
Purity: ≥98%
Potent pan-ERR agonist
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Agonist selective for estrogen-related receptors ERRβ and ERRγ

Chemical Name: N-(4-(Diethylaminobenzylidenyl)-N'-(4-hydroxybenzoyl)-hydrazine
Purity: ≥98%
Agonist selective for estrogen-related receptors ERRβ and ERRγ
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Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes

Chemical Name: 2-[2-(4-Bromophenyl)-1H-benzimidazol-6-yl]-2,3-dihydro-5-(4-morpholinyl)-1H-isoindol-1-one
Purity: ≥98%
Estrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes
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