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5 results for "G9a/GLP Inhibitor Small Molecules and Peptides" in Products
G9a/GLP Inhibitor Small Molecules and Peptides
G9a and GLP (G9a like protein) are histone lysine methyltransferases, also known as euchromatic histone-lysine n-methyltransferase 2 (EMHT2) and EMHT1 respectively. They exist in heteromeric complexes in vivo and lead to transcriptional repression through methylation of H3K9.
G9a or GLP knockout mice exhibit severe retardation during embryonic growth and early lethality, showing G9a/GLP H3K9 methylation is required for embryonic development. Upregulation of G9a/GLP expression is found in ...
| Chemical Name: | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride |
| Purity: | ≥98% |
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| Chemical Name: | 7-[3-(Dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-4-quinazolinamine |
| Purity: | ≥98% |
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| Chemical Name: | 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
| Purity: | ≥98% |
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| Chemical Name: | 2-(4,4-Difluoro-1-piperidinyl)-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine |
| Purity: | ≥98% |
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| Chemical Name: | 5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine |
| Purity: | ≥98% |
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