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3 results for "GABA-B Receptor Modulators Small Molecules and Peptides" in Products
GABA-B Receptor Modulators Small Molecules and Peptides
GABAB receptors are GPCRs composed of seven transmembrane domains and a large extracellular N-terminal, and are responsible for mediating the inhibitory effects of GABA, alongside ionotropic GABAA and GABAA-ρ receptors. They are composed of 850 - 960 amino acids, and are most similar in structure to metabotropic glutamate receptors (mGluRs).
These receptors are heterodimers of GABAB1 and GABAB2 subunits. The GABAB1 subunit hosts the binding site for GABA and other ligands, while the GABAB2...
Positive allosteric modulator of GABAB receptors
| Chemical Name: | 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-β,β-dimethyl-benzenepropanol |
| Purity: | ≥98% |
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Positive allosteric modulator of GABAB receptors
| Chemical Name: | N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine |
| Purity: | ≥98% |
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Potent and selective postitive allosteric modulator of GABAB receptors
| Chemical Name: | 5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone |
| Purity: | ≥98% |
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