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Glutamate (EAAT) Transporter Inhibitors

Glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1) found widely distributed throughout the brain. There are five EAAT subtypes, each with a specific primary distribution; EAAT1 (cerebellar glia), EAAT2 (forebrain glia), EAAT3 (cortical neurons), EAAT4 (cerebellar Purkinje neurons) and EAAT5 (retina).

Functions of glutamate transporters include regulation of excitatory neurotransmission...

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Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist

Chemical Name: 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt
Purity: ≥90%
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
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