2 results for "GPR55 Receptor Antagonists" in Products

GPR55 Receptor Antagonists

GPR55 is a previously orphan receptor that exhibits affinity for endogenous, plant and synthetic cannabinoids, as well as lysophosphatidylinositols (LPIs), which are suggested to be its endogenous ligand. The effects of cannabinoid ligands that are inactive at CB1 and CB2, e.g. palmitoylethanolamide, are thought to be mediated through GPR55.

GPR55 is coupled to both the Gα12/13 and the Gαq intracellular pathways and displays complex pharmacology, with ligands having functional ...

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Potent, selective GPR55 antagonist

Alternate Names: CID 1261822
Chemical Name: N-[4-[[(3,4-Dimethyl-5-isoxazolyl)amino]sulfonyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide
Purity: ≥98%
Potent, selective GPR55 antagonist
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Selective GPR55 antagonist

Chemical Name: 4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid
Purity: ≥98%
Selective GPR55 antagonist
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