4 results for "GR/NR3C1" in Products

GR/NR3C1 Products

Glucocorticoid receptor (GR; NR3C1) is a member of the steroid receptor family. GR are expressed in almost all human tissues and organs. GR bind to its sequences as a homodimer. Two different forms, GR-alpha and GR-beta, differing in their C-terminal parts were isolated. GR-alpha is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GR-beta does not bind glucocorticoids.

Endogenous glucocorticoid

Chemical Name: (11β)-11,21-Dihydroxypregn-4-ene-3,20-dione
Purity: ≥98%
Endogenous glucocorticoid
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Selective high affinity glucocorticoid receptor agonist

Chemical Name: (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid fluoromethyl ester
Purity: ≥98%
Selective high affinity glucocorticoid receptor agonist
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Glucocorticoid receptor agonist

Chemical Name: N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide
Purity: ≥98%
Glucocorticoid receptor agonist
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Glucocorticoid receptor agonist

Chemical Name: 11β,17β,21-Trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione
Purity: ≥98%
Glucocorticoid receptor agonist
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