Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
3 results for "HCN Channel Blockers Small Molecules and Peptides" in Products
HCN Channel Blockers Small Molecules and Peptides
HCN (hyperpolarization-activated, cyclic nucleotide-gated) channels are members of the cyclic nucleotide-regulated channel family along with cyclic nucleotide-gated (CNG) channels. Each channel is made up of four subunits, with each subunit comprising six transmembrane α-helical segments, with the S4 segment thought to be the voltage sensor. They are cation permeable channels that open under hyperpolarization. In contrast to most voltage-gated ion channels, they are constitutively open at ...
Inhibits pacemaker (If) current
| Alternate Names: | ICI D7288 |
| Chemical Name: | 4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride |
| Purity: | ≥98% |
Loading...
HCN channel blocker; inhibits If pacemaker current
| Chemical Name: | 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride |
| Purity: | ≥98% |
Loading...
Blocks hyperpolarization-activated current (If)
| Alternate Names: | UL-FS 49 |
| Chemical Name: | 3-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride |
| Purity: | ≥98% |
Loading...