11 results for "Histone Deacetylase 6/HDAC6 Small Molecules and Peptides" in Products

Histone Deacetylase 6/HDAC6 Small Molecules and Peptides

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor
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Potent histone deacetylase inhibitor

Chemical Name: (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Purity: ≥95%
Potent histone deacetylase inhibitor
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HDAC6 inhibitor; inhibits α-tubulin deacetylation

Chemical Name: N-[4-[(2R,4R,6S)-4-[[(4,5-Diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide
Purity: ≥96%
HDAC6 inhibitor; inhibits α-tubulin deacetylation
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Class I and II HDAC inhibitor

Alternate Names: Vorinostat
Chemical Name: N-Hydroxy-N'-phenyloctanediamide
Purity: ≥98%
Class I and II HDAC inhibitor
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Histone deacetylase inhibitor

Alternate Names: 4-PB,Sodium phenylbutyrate
Chemical Name: 4-Phenylbutyric acid, sodium salt
Purity: ≥98%
Histone deacetylase inhibitor
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HDAC (Class I) inhibitor

Alternate Names: entinostat,SNDX 275
Chemical Name: (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate
Purity: ≥98%
HDAC (Class I) inhibitor
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Potent class I and IIb HDAC inhibitor

Chemical Name: 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide
Purity: ≥98%
Potent class I and IIb HDAC inhibitor
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Dual histone deacetylase (HDAC) 6/8 inhibitor

Chemical Name: N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide
Purity: ≥98%
Dual histone deacetylase (HDAC) 6/8 inhibitor
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Highly potent and selective HDAC2 inhibitor

Chemical Name: Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate
Purity: ≥98%
Highly potent and selective HDAC2 inhibitor
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Pan-histone deacetylase inhibitor

Chemical Name: (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide
Purity: ≥98%
Pan-histone deacetylase inhibitor
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Selective HDAC3 inhibitor; also myelination inducer

Chemical Name: N-(2-Aminophenyl)-5-[(phenylmethyl)amino]-2-pyrazinecarboxamide dihydrochloride
Purity: ≥98%
Selective HDAC3 inhibitor; also myelination inducer
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