3 results for "ICAM-1/CD54 Small Molecules and Peptides" in Products

ICAM-1/CD54 Small Molecules and Peptides

ICAM-1 (intercellular adhesion molecule-1), also known as CD54, is a transmembrane protein that is upregulated on endothelial and epithelial cells at sites of inflammation. It mediates the vascular adhesion and paracellular migration of leukocytes expressing activated LFA-1 (CD11a/CD18) and Mac-1  (CD11b/CD18). It also binds several non-integr...

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Selective inhibitor of E-selectin and ICAM-1 expression

Chemical Name: 4-[(4-Methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide
Purity: ≥98%
Selective inhibitor of E-selectin and ICAM-1 expression
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Potent inhibitor of the LFA-1/ICAM interaction

Chemical Name: 6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4,4]non-7-yl]-3-pyridinecarboxylic acid
Purity: ≥98%
Potent inhibitor of the LFA-1/ICAM interaction
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Potent inhibitor of the LFA-1/ICAM-1 interaction

Chemical Name: (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one
Purity: ≥98%
Potent inhibitor of the LFA-1/ICAM-1 interaction
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