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6 results for "IGF-I R/IGF1R Proteins and Enzymes" in Products
IGF-I R/IGF1R Proteins and Enzymes
IGF-I R/IGF1R (Insulin-like Growth Factor I Receptor), also known as CD221, is a ubiquitously expressed heterotetrameric transmembrane glycoprotein consisting of two alpha and two beta subunits. It binds IGF-1 with high affinity, IGF2 with lower affinity, and Insulin with lowest affinity. IGF1R/Insulin R hybrids respond primarily to IGF-1 and may downregulate cellular responses to Insulin. IGF signaling is also modulated by IGF binding proteins and the scavenger receptor, IGF-II ...
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P08069 |
| Applications: | Binding Activity |
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Analyzed by SEC-MALS
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P08069 |
| Applications: | Binding Activity |
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| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | Q60751 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Source: | HEK293 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Applications: | AC |
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| Applications: | AC |
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