6 results for "Lipid Nanoparticle Components Supplemental Kits and Reagents" in Products

Lipid Nanoparticle Components Supplemental Kits and Reagents

What are Lipid Nanoparticles?

Lipid nanoparticles (LNPs) are lipid based delivery systems commonly used for delivering bioactive nucleic acid payloads into living cells. LNPs are nanometer-sized particles (< 100 nm) comprised of a lipid monolayer shell surrounding an internal core packed with cargo molecules encapsulated in reverse micelles.

Figure 1: Structure and component of lipid nanoparticle carriers. Nucleic acid cargos are stabilized by the ionizable lipids and contained in reverse ...

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Cationic cholesterol derivative

Chemical Name: (3β)-3-[N-[2-(Dimethylamino)ethyl]carbamate cholest-5-en-3-ol hydrochloride
Purity: ≥95%
Cationic cholesterol derivative
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Neutral phospholipid; component of lipid nanoparticles (LNPs)

Alternate Names: 1,2-DSPC
Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphocholine
Purity: ≥95%
Neutral phospholipid; component of lipid nanoparticles (LNPs)
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PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)

Chemical Name: 1,2-Dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000
Purity: ≥90%
PEGylated myristoyl diglyceride; commonly used in the formation of lipid nanoparticles (LNPs)
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Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity

Chemical Name: (3β)-Cholest-5-en-3-ol
Purity: ≥95%
Component of lipid nanoparticles (LNPs); modulator of lipid bilayer fluidity
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Component of lipid nanoparticles (LNPs); ionizable cationic lipid

Chemical Name: (6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate
Purity: ≥95%
Component of lipid nanoparticles (LNPs); ionizable cationic lipid
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PEGylated DSPE with a maleimide reactive group

Chemical Name: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol-2000)]
Purity: ≥90%
PEGylated DSPE with a maleimide reactive group
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