3 results for "Lipoxygenase Inhibitors Small Molecules and Peptides" in Products

Lipoxygenase Inhibitors Small Molecules and Peptides

Lipoxygenases (LOXs) are a family of non-heme iron dioxygenases that are involved in the production and metabolism of fatty acid hydroperoxidases. There are six lipoxygenase isozymes; 5-LOX, 12R-LOX, 12S-LOX, 15-LOX-1 and 15-LOX-2, which catalyze the regio-selective addition of oxygen into arachidonic acid, and epidermal LOX (E-LOX) which metabolizes 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) to a specific epoxyalcohol compound.

Different isozymes have different physiological roles; 5-, 12R...

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Selective 15-lipoxygenase inhibitor

Chemical Name: 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Purity: ≥98%
Selective 15-lipoxygenase inhibitor
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5-LOX inhibitor; orally bioavailable

Alternate Names: ICI D2138
Chemical Name: N-(1-Benzo[b]thien-2-ylethyl)-N-hydroxyurea
Purity: ≥98%
5-LOX inhibitor; orally bioavailable
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Inhibitor of 5-lipoxygenase-activating protein (FLAP)

Alternate Names: L-663,536
Chemical Name: 1-[(4-Chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-α,α-dimethyl-5-(1-methylethyl)-1H-Indole-2-propanoic acid
Purity: ≥98%
Inhibitor of 5-lipoxygenase-activating protein (FLAP)
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