3 results for "MDR1/ABCB1 Small Molecules and Peptides" in Products

MDR1/ABCB1 Small Molecules and Peptides

MDR1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are invo...

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P-gp and BCRP inhibitor

Alternate Names: GF 120918
Chemical Name: N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide hydrochloride
Purity: ≥98%
P-gp and BCRP inhibitor
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Selective MRP1 and P-gp inhibitor

Chemical Name: N-[3-(4-Morpholinyl)propyl]-5,7-diphenylpyrazolo[1,5-a]pyrimidine-3-carboxamide
Purity: ≥95%
Selective MRP1 and P-gp inhibitor
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Potent P-glycoprotein (P-gp) inhibitor

Chemical Name: N-[2-[[[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]amino]carbonyl]-4,5-dimethoxyphenyl]-3-quinolinecarbxamide dihydrochloride
Purity: ≥98%
Potent P-glycoprotein (P-gp) inhibitor
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