SNAP 94847 hydrochloride

  ( 1 citations )    
Product Datasheet
Catalog Number:3347
Chemical Name:N-[3-[1-[[4-(3,4-Difluorophenoxy)phenyl]methyl]-4-piperidinyl]-4-methylphenyl]-2-methylpropanamide hydrochloride
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Potent melanin-concentrating hormone receptor 1 (MCH1) antagonist (Ki = 2.2 nM, KD = 530 pM) that displays > 80-fold and > 500-fold selectivity over α1A and D2 receptors respectively. Increases neurogenesis in the dentate gyrus and decreases food-reinforced operant responding in vivo. Exhibits anxiolytic activity and is orally active.
Technical Data
  • M.Wt:
    515.03
  • Formula:
    C29H32F2N2O2.HCl
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Desiccate at RT
  • CAS No:
    487051-12-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SNAP 94847 hydrochloride include:

1 Citations: Showing 1 - 1

  1. Physical Exercise Counteracts Stress-induced Upregulation of Melanin-concentrating Hormone in the Brain and Stress-induced Persisting Anxiety-like Behaviors.
    Authors: Kim and Han
    Exp Neurobiol  2016;25:163

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