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5 results for "OX1 Receptor Antagonists Small Molecules and Peptides" in Products
OX1 Receptor Antagonists Small Molecules and Peptides
The OX1 receptors, also known as hypocretin receptor 1, are located primarily in the ventromedial hypothalamus, locus coeruleus, median raphe, hippocampus and taenia tecta where they are thought to regulate sleep-wakefulness and energy homeostasis. The OX1 receptor displays higher affinity for Orexin A over Orexin B. The human OX1 receptor gene has been localized to chromosome 1 (1p33).
Selective non-peptide OX1 antagonist
| Chemical Name: | N-(2-Methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl urea |
| Purity: | ≥98% |
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Selective non-peptide OX1 antagonist
| Chemical Name: | N-(6,8-Difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]urea |
| Purity: | ≥98% |
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Potent and selective non-peptide OX1 antagonist
| Chemical Name: | [5-(2-Fluorophenyl)-2-methyl-4-thiazolyl][2(S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl-1-pyrrolidinyl]methanone |
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Potent and selective OX1 antagonist
| Chemical Name: | (aR,1S)-1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-N-(1-methylethyl)-a-phenyl-2(1H)-isoquinolineacetamide |
| Purity: | ≥98% |
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Potent and selective peptide OX1 agonist
| Purity: | ≥95% |
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