5 results for "OXTR Small Molecules and Peptides" in Products
OXTR Small Molecules and Peptides
Oxytocin Receptor (OXTR) is a 60 - 70 kDa 7TM G protein-coupled receptor for the peptide hormone Oxytocin. OXTR plays a role in several aspects of reproductive function including uterine contraction, mammary gland proliferation, and milk ejection in the female and erection and ejaculation in the male. It also promotes natriuresis and the development of male aggression and mother/offspring relationships. OXTR can form homo-oligomers and hetero-oligomers with the Vasopressin receptors V1a and V2. Human OXTR shares 92% aa sequence identity with mouse and rat OXTR.
Involved in uterine contraction and lactation
| Purity: | ≥95% |
Potent, non-peptide oxytocin receptor antagonist
| Chemical Name: | (2S)-2-Amino-N-[(1S,2S,4R)-7,7-dimethyl-1-[[[4-(2-methylphenyl)-1-piperazinyl]sulfonyl]methyl]bicyclo[2.2.1]hept-2-yl]-4-(methylsulfonyl)butanamide dihydrochloride |
| Purity: | ≥97% |
Potent oxytocin receptor antagonist
| Purity: | ≥98% |
Potent non-peptide oxytocin receptor partial agonist; also V1a receptor antagonist
| Chemical Name: | (2S)-N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-2-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)thioxomethyl]-1-pyrrolidinecarboxamide |
| Purity: | ≥97% |
Oxytocin analog
| Purity: | ≥95% |
