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4 results for "PAI-1 Inhibitors Small Molecules and Peptides" in Products
PAI-1 Inhibitors Small Molecules and Peptides
Plasminogen activator inhibitor-1 (PAI-1) is a serine protease inhibitor, encoded by the SERPINE1 gene. High levels of this protein are a risk factor for thrombosis and atherosclerosis, and elevated blood levels are associated with poor clinical outcome and response to therapy in cancer patients.
PAI-1 is the primary regulator of the plasminogen activation system, through its inhibitory action on tissue plasminogen activator (tPA) and urokinase (uPA). Both tPA and uPA cleave plasminogen to ...
| Chemical Name: | 2-[5-[[6-[5-(1,1-Dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]propanedioic acid disodium salt |
| Purity: | ≥98% |
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| Chemical Name: | 5-Chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt |
| Purity: | ≥98% |
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| Alternate Names: | PAI 039,tiplasinin |
| Chemical Name: | α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid |
| Purity: | ≥98% |
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| Chemical Name: | 5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt |
| Purity: | ≥98% |
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