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2 results for "Protease-Activated Receptor Inhibitors Small Molecules and Peptides" in Products
Protease-Activated Receptor Inhibitors Small Molecules and Peptides
Protease-activated receptors (PARs, also known as thrombin receptors) are G-protein-coupled receptors, activated by cleavage of their N-terminal domains by serine proteases. Hydrolysis reveals a tethered peptide ligand, which interacts with the receptor within extracellular loop-2 to affect transmembrane signaling. Four subtypes of receptors have so far been cloned (PAR1-4).
PAR1 is the most well characterized member of this receptor family and is activated by the endogenous serine protease ...
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
| Alternate Names: | FOY |
| Chemical Name: | 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester mesylate |
| Purity: | ≥98% |
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Tryptase inhibitor
| Chemical Name: | N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide |
| Purity: | ≥95% |
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