3 results for "RAR alpha/NR1B1 Small Molecules and Peptides" in Products

RAR alpha/NR1B1 Small Molecules and Peptides

Retinoic Acid Receptor alpha (RAR alpha; NR1B1) is closely related to TR. RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR alpha is expressed in adult skin, and lung. RAR alpha is redundantly involved in vertebrates in the pleiotropic control of embryonic patterning and organogenesis, cell proliferation, differentiation and apoptosis, as well as homeostatic control.

High affinity pan-RAR antagonist

Chemical Name: 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid
Purity: ≥98%
High affinity pan-RAR antagonist
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Selective RARα antagonist

Chemical Name: 4-[5-[8-(1-Methylethyl)-4-phenyl-2-quinolinyl]-1H-pyrrolo-2-benzoic acid
Purity: ≥98%
Selective RARα antagonist
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Potent RXR antagonist

Chemical Name: 4-(7,8,9,10-Tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]-diazepin-12-yl)-benzoic acid
Purity: ≥98%
Potent RXR antagonist
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