3 results for "TGR5/GPBAR1 Small Molecules and Peptides" in Products
TGR5/GPBAR1 Small Molecules and Peptides
TGR5, also called GPBAR1, M-BAR, or BG37 or is a G-protein coupled receptor superfamily member that is a widely expressed cell surface receptor for bile acids. On macrophages, bile acid engagement of TGR5/GPBAR1 suppresses phagocytosis and other functions. Extracellular portions of human TGR5/GPBAR1 show approximately 75% amino acid identity with c...
Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist
| Chemical Name: | (+)-(3β)-3-Hydroxylup-20(29)-en-28-oic acid |
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GPBA receptor (TGR5) agonist
| Chemical Name: | 4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one |
| Purity: | ≥98% |
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Potent and selective GPBA receptor (TGR5) agonist
| Chemical Name: | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone |
| Purity: | ≥98% |
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