10 results for "Thromboxane A2 R/TBXA2R" in Products

Thromboxane A2 R/TBXA2R Products

The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder. The thromboxane A2 receptor is encoded by a single gene that is alternatively spliced at the carboxyl terminus, resulting in two variants, TP (343 residues) and TP (407 residues) that share the first 328 amino acids.

Reactivity: Human
Applications:
R&D Systems VersaClone cDNA Plasmids
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Reactivity: Human, Rat
Details: Rabbit Polyclonal
Applications: WB
Thromboxane A2 R/TBXA2R Antibody
(3)
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #SR1893
Applications: WB
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Reactivity: Human
Applications: WB
Western Blot: Thromboxane A2 R/TBXA2R Overexpression Lysate [NBL1-16752]
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Reactivity: Human
Details: Rabbit Polyclonal
Applications: WB
Western Blot: Thromboxane A2 R/TBXA2R Antibody [NBP3-10561]
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Reactivity: Human
Sensitivity: 0.055 ng/mL (example only; lot dependent)
Assay Range: 0.156 - 10 ng/mL (example only; lot dependent)
Applications: ELISA
Human Thromboxane A2 R/TBXA2R - Ready-To-Use ELISA Kit (Colorimetric)
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Reactivity: Human
Sensitivity: 0.055 ng/mL (example only; lot dependent)
Assay Range: 0.156 - 10 ng/mL (example only; lot dependent)
Applications: ELISA
Human Thromboxane A2 R/TBXA2R ELISA Kit (Colorimetric)
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Potent, stable thromboxane A2 (TP) receptor agonist

Alternate Names: 9,11-Dideoxy-9a,11a-methanoepoxy prostaglandin F2a
Chemical Name: (5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid
Purity: ≥98%
Potent, stable thromboxane A2 (TP) receptor agonist
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Potent thromboxane A2 (TP) antagonist

Alternate Names: terutroban
Chemical Name: (6R)-6-[[(4-Chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-1-naphthalenepropanoic acid
Purity: ≥98%
Potent thromboxane A2 (TP) antagonist
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Dual TP/DP2 (CRTH2) receptor antagonist

Alternate Names: Ramatroban
Chemical Name: (3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoic acid
Purity: ≥98%
Dual TP/DP2 (CRTH2) receptor antagonist
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