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2 results for "Thymidylate Synthetase Inhibitor" in Products
Thymidylate Synthetase Inhibitor
Thymidylate Synthetase (TS) EC 2.1.1.45 is a highly conserved bifunctional enzyme, that catalyzes the conversion of deoxyuridine monophosphate (dUMP) and 5,10-methylenetetrahydrofolate to deoxythymidine monophosphate (dTMP) and dihydrofolate. This is an essential metabolic reaction, producing dTMP required for DNA synthesis and dihydrofolate, required for production of purines and pyrimidines and therefore DNA and RNA.
TS also functions as a RNA binding protein, able to regulate its own protein ...
Thymidylate synthetase inhibitor
| Alternate Names: | 5-FU |
| Chemical Name: | 5-Fluoro-2,4-(1H,3H)-pyrimidinedione |
| Purity: | ≥98% |
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Thymidylate synthetase inhibitor, also inhibits dihydrofolate reductase, GARFT and AICART
| Chemical Name: | N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid |
| Purity: | ≥98% |
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