6 results for "YAP/TAZ Signaling Inhibitors" in Products
YAP/TAZ Signaling Inhibitors
The Hippo signaling pathway regulates cell proliferation and differentiation, playing a key role in the regulation of tissue development and organ size through restriction of proliferation and promotion of apoptosis. First identified in Drosophila melanogaster, this pathway is conserved in mammals and regulates transcription of a wide range of genes through the interaction of the Yes associated protein (YAP)/Transcriptional coactivator with PDZ binding domain (TAZ) complex with transciptional ...
YAP inhibitor
| Alternate Names: | Visudyne |
| Chemical Name: | (4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid monomethyl ester |
| Purity: | ≥95% |
Potent and selective SETD7 inhibitor
| Chemical Name: | 8-Fluoro-1,2,3,4-tetrahydro-N-[(1R)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride |
| Purity: | ≥97% |
Potent and selective MST1/2 inhibitor; orally bioavailable
| Chemical Name: | 4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide |
| Purity: | ≥98% |
YAP inhibitor
| Purity: | ≥95% |
Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling
| Chemical Name: | 4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide |
| Purity: | ≥98% |
Potent pan-TEAD inhibitor
| Chemical Name: | N-[(1S)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide |
| Purity: | ≥98% |
