APPL Antibody (S05-8D5)

Name: APPL Antibody (S05-8D5)
Brand: Novus Biologicals
SKU: NBP3-14998
Price: 479 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-14998

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Product Documents

Recombinant Monoclonal Antibody

100% Guarantee

Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S05-8D5 expressed in HEK293

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Product Specifications

Immunogen

A synthetic peptide of human APPL (Uniprot#: Q9UKG1)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

80 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

Novus Biologicals Rabbit APPL Antibody (S05-8D5) (NBP3-14998) is a recombinant monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for APPL Antibody (S05-8D5)

Western Blot: APPL Antibody (S05-8D5) [NBP3-14998]

Western Blot: APPL Antibody (S05-8D5) [NBP3-14998] - Western blot detection of APPL in Rat Brain, C6, 3T3, Hela cell lysates using APPL Rabbit mAb (1:1000 diluted). Predicted band size: 80kDa. Observed band size: 80kDa.

Immunohistochemistry-Paraffin: APPL Antibody (S05-8D5) [NBP3-14998]

Immunohistochemistry-Paraffin: APPL Antibody (S05-8D5) [NBP3-14998] - Immunohistochemistry of APPL in paraffin-embedded Human lung cancer tissue using APPL Rabbit mAb at dilution 1/20

Applications for APPL Antibody (S05-8D5)

Application

Recommended Usage

Immunohistochemistry

1/20

Western Blot

1/1000-1/5000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: APPL

APPL is encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Long Name

Adapter Protein Containing PH Domain PTB Domain and Leucine Zipper Motif 1

Alternate Names

APPL1, DIP13A

Gene Symbol

APPL1

Additional APPL Products

Product Documents for APPL Antibody (S05-8D5)

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Product Specific Notices for APPL Antibody (S05-8D5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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