Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # B-E5

Format

Azide and BSA Free
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Product Specifications

Immunogen

Daudi cell line

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Stable at 4C for 12 months.

Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Scientific Data Images for CD21 Antibody (B-E5) - Azide and BSA Free

Flow Cytometry: CD21 Antibody (B-E5) - Azide and BSA Free [NBP3-14587]

Flow Cytometry: CD21 Antibody (B-E5) - Azide and BSA Free [NBP3-14587]

Flow Cytometry: CD21 Antibody (B-E5) [NBP3-14587] - A typical staining pattern with the B-E5 monoclonal antibody of lymphocytes.

Applications for CD21 Antibody (B-E5) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Biological Activity: Induces human B-cell proliferation and competes with EBV for CD21 binding.

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Advanced Features

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  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. Sterile-filtered through 0.22 um.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD21

CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.

Alternate Names

C3DR, CD21, CR2

Gene Symbol

CR2

Additional CD21 Products

Product Documents for CD21 Antibody (B-E5) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for CD21 Antibody (B-E5) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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