CD45RC Antibody (RM291)

Novus Biologicals | Catalog # NBP2-61512

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM291 expressed in HEK293
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Product Specifications

Immunogen

A peptide corresponding to the C-terminus of Human CD45RC

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD45RC Antibody (RM291)

Western Blot: CD45RC Antibody (RM291) [NBP2-61512] -

Western Blot: CD45RC Antibody (RM291) [NBP2-61512] - Western Blot of Jurkat cell lysates using NBP2-61512 at a 1:2000 dilution
Immunohistochemistry-Paraffin: CD45RC Antibody (RM291) [NBP2-61512]

Immunohistochemistry-Paraffin: CD45RC Antibody (RM291) [NBP2-61512]

Immunohistochemistry-Paraffin: CD45RC Antibody (RM291) [NBP2-61512] - Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue sections using NBP2-61512 at a 1:400 dilution.
Immunohistochemistry-Paraffin: CD45RC Antibody (RM291) [NBP2-61512]

Immunohistochemistry-Paraffin: CD45RC Antibody (RM291) [NBP2-61512]

Immunohistochemistry-Paraffin: CD45RC Antibody (RM291) [NBP2-61512] - Immunohistochemical staining of formalin fixed and paraffin embedded human liver tissue sections using NBP2-61512 at a 1:400 dilution.

Applications for CD45RC Antibody (RM291)

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:200

Western Blot

1:1000-1:2000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CD45RC

The CD45 family of cell surface glycoprotein antigens exist as a set of isoforms. The patterns of monoclonal antibody recognition of the CD45 phenotypes can be restricted (CD45RA, RB and RC), or broader, such as the CD45 T 200 species. The "restricted" subsets of this group arise as a result of translation of alternatively spliced mRNAs from exons A, B and C (exons 4, 5 and 6), where exons 3-15 encode the extracellular domain of the CD45 molecule. The restricted epitopes are differentially expressed on T and B lymphocytes, including functionally distinct T cells. CD45 (LCA) is a transmembrane phosphotyrosine phosphatase expressed on leucocytes. Myeloid cells do not express the RC isoform.

Alternate Names

B220, CD45 antigen, CD45R, EC 3.1.3.48, L-CA, LY5, protein tyrosine phosphatase, receptor type, C, receptor-type tyrosine-protein phosphatase C, T200 glycoprotein, T200 leukocyte common antigen, T200receptor type, c polypeptide

Gene Symbol

PTPRC

Additional CD45RC Products

Product Documents for CD45RC Antibody (RM291)

Certificate of Analysis

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Product Specific Notices for CD45RC Antibody (RM291)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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