Complement C3d Antibody (E28-P)

Novus Biologicals | Catalog # NBP1-79074

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

ELISA

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # E28-P
View all Complement C3d Primary Antibodies »

Product Specifications

Immunogen

Peptide derived from N-terminal sequence of human Complement C3d fragment.

Reactivity Notes

Mouse reactivity may be low or non-existant. Initial results based on customer testing. Please see our product reviews for more information.

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Scientific Data Images for Complement C3d Antibody (E28-P)

Immunohistochemistry-Paraffin: Complement C3d Antibody (E28-P) [NBP1-79074]

Immunohistochemistry-Paraffin: Complement C3d Antibody (E28-P) [NBP1-79074]

Immunohistochemistry-Paraffin: Complement C3d Antibody (E28-P) [NBP1-79074] - Formalin-fixed and paraffin-embedded human skin biopsy (4 um) from lesion of the early pemphigus vulgaris (without blister formation), stained with anti-C3d complement antibody shows strong positive intraepidermal intercellular immunostaining.

Applications for Complement C3d Antibody (E28-P)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:100-1:200

Reviewed Applications

Read 1 review rated 1 using NBP1-79074 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

20mM Tris-HCl (pH 8.0) and 20mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Complement C3d

C3d is a fragment of the major complement protein C3, C3d is formed as a result of the deactivation of C3b.Factor I in the presence of cofactors cleaves C3b to form iC3b and C3f, Factor I and/or other proteasesthen cleaves iC3b to form C3c and C3dg. C3dg is then further cleaved by tryptic enzymes to C3g andC3d. The C3 fragments are then eliminated from circulation by phagocytic cells in the liver. C3d has amolecular weight of 34kDa. Normally C3d is present in trace amounts in plasma, however, in diseasestates where rapid complement consumption is occurring levels of C3d can be elevated.

Alternate Names

AHUS5, ARMD9, ASP, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, complement C3, complement component 3, complement component C3, CPAMD1acylation-stimulating protein cleavage product

Gene Symbol

C3

UniProt

P01024

Additional Complement C3d Products

Product Documents for Complement C3d Antibody (E28-P)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Complement C3d Antibody (E28-P)

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Complement C3d Antibody (E28-P)

Customer Reviews for Complement C3d Antibody (E28-P) (1)

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  • Complement C3d Antibody (E28-P)
    Name: Anonymous
    Application: Immunohistochemistry-Paraffin
    Sample Tested: Diseased kidney
    Species: Mouse
    Verified Customer | Posted 12/20/2016
    This is a representative image of the Novus rabbit monoclonal to C3d in a diseased mouse kidney paraffin section:
    Note: This customer submitted a review in an untested species (mouse) I tried the antibody NBP1-79074 at a dilution of 1:10 using three different epitope retrieval methods: a) HiER with citrate, b) HiER in alkaline Tris, and c) enzymatic pre-treatment with Proteinase K. I saw no signal under any conditions.
    Complement C3d Antibody (E28-P) NBP1-79074

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