Derlin-2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-49231

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
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Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GIRILKTPSILKAIFDTPDEDPN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Derlin-2 Antibody - BSA Free

Immunohistochemistry: Derlin-2 Antibody [NBP2-49231]

Immunohistochemistry: Derlin-2 Antibody [NBP2-49231]

Immunohistochemistry: Derlin-2 Antibody [NBP2-49231] - Staining of human lymph node shows strong cytoplasmic positivity in subset of germinal and non-germinal center cells.

Applications for Derlin-2 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Derlin-2

DERL2 (Derlin 2) may be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. Its precise role is however unclear. In contrast to DER1, it is not involved in the degradation of MHC class I heavy chains in cas of infection by the cytomegalovirus. DERL2 may play a role in cell proliferation.

Alternate Names

carcinoma related, Degradation in endoplasmic reticulum protein 2, Der1-like domain family, member 2, Der1-like protein 2, DER2, derlin-2, F-LAN-1DERtrin-2, FLANa, F-LANaCGI-101

Gene Symbol

DERL2

Additional Derlin-2 Products

Product Documents for Derlin-2 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Derlin-2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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