DP1 Antibody (8C0O3)

Novus Biologicals | Catalog # NBP3-16590

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 8C0O3 expressed in HEK293
View all DP1 Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 311-410 of human DP1 (Q14186). SGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVFITTAGSTSNGTRFSASDLTNGADGMLATSSNGSQYSGSRVETPVSYVGEDDEEDDDFNENDEDD

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for DP1 Antibody (8C0O3)

Western Blot: DP1 Antibody (8C0O3) [NBP3-16590]

Western Blot: DP1 Antibody (8C0O3) [NBP3-16590]

Western Blot: DP1 Antibody (8C0O3) [NBP3-16590] - Western blot analysis of extracts of various cell lines, using DP1 Rabbit mAb (NBP3-16590) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Immunohistochemistry-Paraffin: DP1 Antibody (8C0O3) [NBP3-16590]

Immunohistochemistry-Paraffin: DP1 Antibody (8C0O3) [NBP3-16590]

Immunohistochemistry-Paraffin: DP1 Antibody (8C0O3) [NBP3-16590] - Immunohistochemistry of paraffin-embedded human esophageal using DP1 Rabbit mAb (NBP3-16590) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Immunohistochemistry-Paraffin: DP1 Antibody (8C0O3) [NBP3-16590]

Immunohistochemistry-Paraffin: DP1 Antibody (8C0O3) [NBP3-16590]

Immunohistochemistry-Paraffin: DP1 Antibody (8C0O3) [NBP3-16590] - Immunohistochemistry of paraffin-embedded rat ovary using DP1 Rabbit mAb (NBP3-16590) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Applications for DP1 Antibody (8C0O3)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol, 0.05% BSA

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: DP1

The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 forms heterodimers with a second protein, designated DP-1, forming an

Alternate Names

DP1E2F dimerization partner 1, DRTF1Dp-1, DRTF1-polypeptide 1, E2F-related transcription factor, transcription factor Dp-1

Gene Symbol

TFDP1

Additional DP1 Products

Product Documents for DP1 Antibody (8C0O3)

Certificate of Analysis

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Product Specific Notices for DP1 Antibody (8C0O3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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