Frizzled-5 Antibody [Biotin]

Name: Frizzled-5 Antibody [Biotin]
Brand: Novus Biologicals
SKU: NBP3-73952

Novus Biologicals | Catalog # NBP3-73952

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Product Documents

Fc Region Site-Specific Biotinylated Antibody

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (91%), Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG

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Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: WPERMSCDRLPVLGRDAEVLCMDYNRSEATTAPPRPFPAKPTLP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. Successful site-specific biotin conjugation is confirmed by reducing SDS-PAGE, revealing a mobility shift of the antibody heavy-chain when biotin is covalently attached. Additional information may be available upon request. The antibody concentration is provided on the individual product label. For specialized conjugation needs, like large quantities, and specific concentrations, bulk and custom antibody conjugation services are available.

Applications for Frizzled-5 Antibody [Biotin]

Application

Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Recommended applications and dilutions are based on validated applications from the unconjugated base product NBP1-70338.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

40% glycerol and PBS (pH 7.2).

Preservative

0.02% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Frizzled-5

FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. FZD5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. FZD5 was cloned from a retina cDNA library.

Alternate Names

Frizzled5, Frz-5, FZ-5, FZD5

Gene Symbol

FZD5

Additional Frizzled-5 Products

Product Documents for Frizzled-5 Antibody [Biotin]

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Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for Frizzled-5 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Wnt Family

Wnt Receptors

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