GnRHR Antibody (LCHR37)

Name: GnRHR Antibody (LCHR37)
Brand: Novus Biologicals
SKU: NBP3-27924
Price: 899 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-27924

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Product Documents

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ kappa Clone # LCHR37

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Product Specifications

Immunogen

Recombinant full-length human protein was used as the immunogen for the GnRHR antibody.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁ kappa

Description

Novus Biologicals Mouse GnRHR Antibody (LCHR37) (NBP3-27924) is a monoclonal antibody validated for use in IHC and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for GnRHR Antibody (LCHR37)

Immunohistochemistry: GnRHR Antibody (LCHR37) [NBP3-27924] -

Immunohistochemistry: GnRHR Antibody (LCHR37) [NBP3-27924] - IHC testing of FFPE human ovarian carcinoma and GnRHR antibody (clone LCHR37)

Applications for GnRHR Antibody (LCHR37)

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

1 - 2 ug/ml

Immunohistochemistry-Paraffin

1 - 2 ug/ml

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, 0.1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: GnRHR

GnRHR encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.

Long Name

Gonadotropin-releasing Hormone Receptor

Alternate Names

GNRHR1, GRHR, HH7, LHRHR, LRHR, Luliberin

Gene Symbol

GNRHR

UniProt

P30968 (Human)

Additional GnRHR Products

Product Documents for GnRHR Antibody (LCHR37)

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Product Specific Notices for GnRHR Antibody (LCHR37)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Neurotransmitter G Protein-Coupled Receptors

Peptide Hormone G Protein-Coupled Receptors

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