Human Aquaporin 4/AQP4 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB11659S Datasheet / COA / SDS

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FAB11659S-100UG

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Human Aquaporin 4/AQP4 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects a synthetic peptide specific for human Aquaporin-4 around aa 315 in Direct ELISA.

Source

Monoclonal Mouse IgG Clone # 1093722

Purification

Protein A or G purified

Immunogen

Synthetic Peptide
Accession # P55087

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Aquaporin 4/AQP4

Aquaporin 4, AQP4, is a 35kDa water channel protein that plays an important role in brain water homeostasis. AQP4 is highly expressed in the end feet of astrocytes in the brain and CNS with the largest presence in the cerebellum and spinal cord grey matter. It can also be located in epithelial cells of many organs throughout the body. The main function of AQP4 is to provide fast water transportation and homeostatic balance throughout the central nervous system.

Long Name

Aquaporin 4

Entrez Gene IDs

361 (Human)

Alternate Names

AQP4; AQP-4; Aquaporin 4; MGC22454; MIWC; WCH4