Human Arylsulfatase B/ARSB Alexa Fluor® 405-conjugated Antibody

Catalog #: AF4415V Datasheet / COA / SDS

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AF4415V-100UG

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Human Arylsulfatase B/ARSB Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Arylsulfatase B/ARSB in Western blots.

Source

Polyclonal Sheep IgG

Purification

Antigen Affinity-purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Arylsulfatase B/ARSB
Ser37-Met533 (Val376Met)
Accession # P15848

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Arylsulfatase B/ARSB

ARSB, also known as N-acetylgalactosamine-4-sulfatase, is a lysosomal glycoprotein and one of at least nine human arylsulfatases that catalyze the hydrolysis of sulfate ester bonds. ARSB deficiency is causative of the lysosomal storage disease Mucopolysaccharidosis VI. Human ARSB is cleaved intracellularly into fragments which remain associated with a disulfide linkage. Mature human ARSB (aa 37-533) shares 80% amino acid sequence identity with mouse and rat ARSB.

Entrez Gene IDs

411 (Human); 11881 (Mouse); 25227 (Rat)

Alternate Names

ARSB; Arylsulfatase B; ASB; EC 3.1.6.12; G4S; MPS6; N-acetylgalactosamine-4-sulfatase