Human Cerebellin-2 Alexa Fluor® 700-conjugated Antibody

Catalog #: FAB70441N Datasheet / COA / SDS

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FAB70441N-100UG

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Human Cerebellin-2 Alexa Fluor® 700-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Cerebellin-2 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) Cerebellin-1 and rhCerebellin-4 is observed, and approximately 50% cross-reactivity with rhCerebellin-3 is observed.

Source

Monoclonal Mouse IgG1 Clone # 704323

Purification

Protein A or G purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Cerebellin-2
Arg50-Leu224
Accession # Q8IUK8

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 700 (Excitation= 675-700 nm, Emission= 723 nm)

Applications

Recommended Concentration

Sample

Immunohistochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Cerebellin-2

Cerebellin-2 (CBLN2) is an approximately 25 kDa glycoprotein in the Cerebellin family of C1q- and TNF-related proteins. It contains a potential membrane-associating segment but may also be secreted. It contains one C1q-like domain in its extracellular region. Cerebellin-2 expression is developmentally regulated in the cerebellum, neocortex, sensory neurons of the dorsal root ganglion and spinal cord, and adrenal cortex. It associates with Cerebellin-1 which is involved in the formation and maintenance of synapses in the cerebellum. Within the ectodomain (aa 50-224), Human Cerebellin-2 shares 99% aa sequence identity with mouse and rat Cerebellin‑2.

Entrez Gene IDs

147381 (Human); 12405 (Mouse); 291388 (Rat)

Alternate Names

CBLN2; cerebellin 2 precursor; Cerebellin2; Cerebellin-2